Open AccessCutaneous perivascular epithelioid cell tumors: A review on an infrequent neoplasm
Author(s) -
Mar LlamasVelasco,
Luís Requena,
Thomas Mentzel
Publication year - 2016
Publication title -
world journal of methodology
Language(s) - English
Resource type - Journals
ISSN - 2222-0682
DOI - 10.5662/wjm.v6.i1.87
Subject(s) - perivascular epithelioid cell , pathology , immunohistochemistry , epithelioid cell , differential diagnosis , mesenchymal stem cell , neoplasm , medicine , biology
"Perivascular epithelioid cutaneous" cell tumors (PEComa) are a family of mesenchymal tumors with shared microscopic and immunohistochemical properties: They exhibit both smooth muscle cell and melanocytic differentiation. Non-neoplastic counterpart of PEComa's cells are unknown, as well as the relationship between extracutaneous PEComa and primary cutaneous ones. We will review the clinical setting, histopathologic features, chromosomal abnormalities, differential diagnosis and treatment options for cutaneous PEComa.