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Isolation and Antibacterial Properties of Phenyl Acrylic Acid Derivatives from Balanophora elongata Blume
Author(s) -
Dаyаr Аrbаin,
Amri Bakhtiar,
Nova Syafni,
Nofrizal Nofrizal,
Goldha Faroliu,
Nanda Putra
Publication year - 2021
Publication title -
journal of mathematical and fundamental sciences/journal of mathematical and fundamental siences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 12
eISSN - 2337-5760
pISSN - 2338-5510
DOI - 10.5614/j.math.fund.sci.2021.53.2.5
Subject(s) - agar diffusion test , agar , nuclear chemistry , acrylic acid , caffeic acid , bacteria , antibacterial activity , staphylococcus aureus , chloramphenicol , chemistry , streptococcus mutans , biology , organic chemistry , polymer , antioxidant , genetics , monomer
Balanophora elongata (Balanophoraceae) is a tropical parasitic flowering plant 9 cm in height. Four known phenyl acrylic acid derivatives, methyl caffeate (1), caffeic acid (2), 1,6-di-O-caffeoyl-β-D-glucopyranose (3), and coniferin (4), were isolated from this plant. Structural elucidation of the isolated compounds was determined by IR, LC-ESI-MS, 1D and 2D NMR.  Extracts and isolated compounds were tested toward some standard human pathogenic bacteria using the agar disk diffusion method. Their inhibition zones were compared to that of chloramphenicol as positive control. Compound 1 showed inhibition toward Streptococcus mutans, while compound 3 and 4 inhibited Staphylococcus aureus.

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