Open AccessPregabalin as a probable cause of central serous chorioretinopathy: Two case reports
Author(s) -
Yusuf Emre Doğan,
Kübra Neslihan Kurt Oktay,
Yelda Buyru Özkurt,
İ̇lknur Aktaş
Publication year - 2021
Publication title -
turkish journal of physical medicine and rehabilitation :
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.235
H-Index - 5
ISSN - 2587-1250
DOI - 10.5606/tftrd.2021.5433
Subject(s) - pregabalin , medicine , serous fluid , peripheral edema , macular edema , adverse effect , edema , ophthalmology , retinal , anesthesia , surgery
Pregabalin is commonly used for the treatment of neuropathic pain and is attributed to adverse effects of peripheral vasodilation and peripheral edema. Central serous chorioretinopathy (CSCR) is characterized by choroidal fluid leaks from choroidal vessels under the retina, causing focal retinal detachment with macular vision loss. Herein, we report two cases admitted to our clinic with vision loss while under pregabalin treatment. Upon eye examination, both patients were diagnosed with acute CSCR. Pregabalin treatment was discontinued upon the diagnosis of CSCR. We consider that the use of pregabalin in the presented two cases may be the causal effect of the CSCR diagnosis, as pathophysiology of CSCR is in parallel with the edema-related adverse effects of pregabalin.