Open AccessThe role of immune system cells and their receptors in viral infections – selected data
Author(s) -
Joanna Śliwa-Dominiak,
Beata Tokarz–Deptuła,
Wiesław Deptuła
Publication year - 2014
Publication title -
postępy higieny i medycyny doświadczalnej
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 34
eISSN - 1732-2693
pISSN - 0032-5449
DOI - 10.5604/17322693.1098150
Subject(s) - immune system , humoral immunity , biology , immunology , immunity , antibody , receptor , virology , host (biology) , phagocytosis , cellular immunity , genetics
The study of the immune system started about a hundred years ago with the phagocytosis experiments of Mechnikov. That which is now referred to as non-specific cell-mediated immunity was quickly linked to studies related to, inter alia, the immunity determined by antibodies (humoral), which has long been considered as the first line of defense against diseases caused by micro-organisms, including viruses. Despite their small size, viruses have a huge impact on the host, as they produce substances that stimulate the antiviral response and affect it. The paper presents selected data on participation of immune system cells and their receptors in viral infections, as the host cells have evolved a number of specific cellular and humoral components of the signaling networks that are involved in the detection and the host's response to viral infections.