Open AccessSea-buckthorn (Hippophae rhamnoides L.) as a source of compounds with antitumor and radioprotective activity
Author(s) -
Karolina Ulanowska,
Bartosz Skalski,
Beata Olas
Publication year - 2018
Publication title -
postępy higieny i medycyny doświadczalnej
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 34
eISSN - 1732-2693
pISSN - 0032-5449
DOI - 10.5604/01.3001.0011.7481
Subject(s) - hippophae rhamnoides , chemistry , aflatoxin , carcinogen , pharmacology , biology , biochemistry , food science
This work presented characteristics of sea buckthorn (H. rhamnoides), the bioactive compounds they contain and their pro-health, anti-cancer and radioprotective activity. Studies have shown that antioxidants contained in the fruits of plant, such as vitamins A, E and phenolic compound, reduce oxidative damage and also inhibit the formation of carcinogenic compounds, such as aflatoxin B1 or N-nitrosamide. Bioactive substances included in sea buckthorn inhibit the growth and proliferation of malignant cells in a variety of systems: digestive, respiratory, reproductive, blood circulation and lymphatic. In addition, experiments conducted on mice and rats demonstrated the effect of sea buckthorn extracts on the apoptosis of the lung, breast, sarcoma, melanoma and lymphoid leukemia tumor cells.