Open AccessA clinical case of diagnosis of breast cancer in patients with family history of BRCA mutations 1
Author(s) -
М А Айтмагамбетова,
Г А Смагулова,
Yerbol Bekmukhambetov,
Oksana Zavalyonnaya,
Anar Tulyaeva
Publication year - 2021
Publication title -
reports of practical oncology and radiotherapy
Language(s) - English
Resource type - Journals
eISSN - 2083-4640
pISSN - 1507-1367
DOI - 10.5603/rpor.a2021.0069
Subject(s) - breast cancer , daughter , medicine , family history , incidence (geometry) , brother , oncology , cancer , disease , genetic predisposition , male breast cancer , gynecology , biology , physics , evolutionary biology , sociology , anthropology , optics
The incidence of breast cancer is growing rapidly worldwide (1.7 million new cases and 600,000 deaths per year). Moreover, about 10% of breast cancer cases occur in young women under the age of 45. The aim of the study was to report a rare case of BRCA 1-mutated breast cancer in a young patient with multiple affected relatives. Breast cancer is due to a genetic predisposition with BRCA1 and BRCA2 representing a significant proportion of families with a very high risk of developing the disease over a lifetime of up to 50-80%.