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Is deep brain stimulation effective in Huntington’s Disease? — a systematic literature review
Author(s) -
Justyna Kaczyńska,
Emilia J. Sitek,
Grzegorz Witkowski,
Monika Rudzińska,
Piotr Janik,
Jarosław Sławek,
Edeth Maria Garszia Edwin,
Daniel Zielonka
Publication year - 2022
Publication title -
neurologia i neurochirurgia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 26
eISSN - 1897-4260
pISSN - 0028-3843
DOI - 10.5603/pjnns.a2022.0050
Subject(s) - deep brain stimulation , chorea , medicine , huntington's disease , disease , neuromodulation , cognition , rating scale , systematic review , physical medicine and rehabilitation , movement disorders , physical therapy , psychiatry , medline , stimulation , parkinson's disease , psychology , developmental psychology , political science , law
Huntington's Disease (HD) is an autosomal dominant neurodegenerative disorder. Substantial for a diagnosis of the disease are motor disorders, with chorea as a hallmark symptom. Other disease manifestations include cognitive dysfunction and psychiatric disorders. Currently, pharmacological treatment plays the most important role in the therapy of HD patients. However, deep brain stimulation (DBS) is considered a potential therapeutic option.

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