Open AccessThe expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer
Author(s) -
Sebastian Szubert,
Rafał Moszyński,
Dariusz Szpurek,
Bartlomiej Romaniuk,
Stefan Sajdak,
Michał Nowicki,
Sławomir Michalak
Publication year - 2019
Publication title -
ginekologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 21
eISSN - 2543-6767
pISSN - 0017-0011
DOI - 10.5603/gp.a2019.0045
Subject(s) - medicine , ovarian cancer , receptor , correlation , oncology , cancer , cancer research , bioinformatics , biology , geometry , mathematics
The main aim of the study was to investigate the expression of Platelet-Derived Growth Factor Receptors alpha (PDGFR-alpha) and beta (PDGFR-beta) in malignant and benign ovarian tumors. We performed an analysis of the correlation of PDGFRs expression and stage of the disease, tumor grade and histopathological type of epithelial ovarian cancer (EOC). Additionally, we evaluated patient prognosis according to PDGFR expression.