Open AccessPotential therapeutic role of microvesicles derived from mesenchymal stem cells and platelet-rich plasma in murine burn wound healing: scar regulation and antioxidant mechanism
Author(s) -
R A Imam,
Mohamed Amer
Publication year - 2023
Publication title -
folia morphologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1644-3284
pISSN - 0015-5659
DOI - 10.5603/fm.a2022.0060
Subject(s) - mesenchymal stem cell , wound healing , platelet rich plasma , scars , stem cell , microvesicles , medicine , myofibroblast , burn injury , immune system , immunology , pathology , platelet , microbiology and biotechnology , chemistry , microrna , biology , surgery , fibrosis , biochemistry , gene
Microvesicles (MVs) derived from mesenchymal stem cells exhibited an emerging promising therapy in many animal model diseases. Post-burn scars represent one of the significant challenges in wound healing processes. The present study investigated the possible role of MVs derived from mesenchymal stem cells vs. platelet-rich plasma (PRP) in murine burn wound healing.