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The relationship between the aggrecan VNTR polymorphism and its content in lumbar intervertebral discs
Author(s) -
Przemysław A. Pękala,
Dominik Felkle,
Kacper Dykas,
Anna Jarosz,
Pierre Elnazir,
Tomasz Konopka,
Jerzy Walocha,
Joanna Dulińska-Litewka
Publication year - 2022
Publication title -
folia morphologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1644-3284
pISSN - 0015-5659
DOI - 10.5603/fm.a2022.0019
Subject(s) - aggrecan , genotyping , allele , polymorphism (computer science) , genetics , biology , gene , heterozygote advantage , genotype , medicine , pathology , articular cartilage , osteoarthritis , alternative medicine
There is a specific polymorphism of the ACAN gene called the variable number of tandem repeats (VNTR), which is particularly interesting in the light of the development of intervertebral disc pathology and associated low back pain.

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