Effect of preservative-free and preserved prostaglandin analogues on the histology of cornea of adult male guinea pigs following repeated exposure | Zendy

Alshimaa Ali | Zendy; Rasha Salama | Zendy; Mahmoud A. Soliman | Zendy

Open Access

Effect of preservative-free and preserved prostaglandin analogues on the histology of cornea of adult male guinea pigs following repeated exposure

Author(s) -

Alshimaa Ali,

Rasha Salama,

Mahmoud A. Soliman

Publication year - 2021

Publication title -

folia morphologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.333

H-Index - 30

eISSN - 1644-3284

pISSN - 0015-5659

DOI - 10.5603/fm.a2020.0146

Subject(s) - latanoprost , glaucoma , guinea pig , cornea , benzalkonium chloride , prostaglandin , corneal epithelium , ophthalmology , epithelium , travoprost , prostaglandin analogue , medicine , chemistry , pathology

Glaucoma is a group of eye diseases that can cause vision loss. Prostaglandin analogues (PGAs) are known to be first-line treatment for patients with glaucoma. Latanoprost is a good, efficient and well-tolerated PGA that is currently available as latanoprost with benzalkonium chloride (BAC) (Xalatan) and preservative-free (PF) prostaglandin analogue latanoprost (Monopost). Lately, using PF anti-glaucoma agents has been considered an essential procedure for enhancing glaucoma care. This study aimed to analyse the histological changes within the corneal tissue with the use of currently available preserved prostaglandins-derived eye drops and PF prostaglandin analogue.

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