Open AccessShort-term fenofibrate treatment improves ultrastructure of hepatocytes of old rats
Author(s) -
Adrian Zubrzycki,
Agata Wrońska,
Agata Zauszkiewicz-Pawlak,
Zbigniew Kmieć
Publication year - 2021
Publication title -
folia histochemica et cytobiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.384
H-Index - 40
eISSN - 1897-5631
pISSN - 0239-8508
DOI - 10.5603/fhc.a2021.0018
Subject(s) - lipid droplet , oil red o , ultrastructure , peroxisome , glycogen , mitochondrion , hepatocyte , staining , endocrinology , parenchyma , autophagy , medicine , chemistry , lipid metabolism , biology , andrology , biochemistry , pathology , anatomy , adipose tissue , apoptosis , in vitro , receptor , adipogenesis
Fenofibrate (FN) is a hypolipemic drug used for the treatment of mixed dyslipidemia. Since in our previous study FN administration to young and old rats adversely affected the serum activity of liver marker enzymes, we decided to examine the effects of FN on liver ultrastructure of young and old animals.