Open AccessGolgi α-mannosidase II mediates the formation of vascular smooth muscle foam cells under inflammatory stress
Author(s) -
Kelan Zha,
Qiang Ye
Publication year - 2021
Publication title -
folia histochemica et cytobiologica
Language(s) - English
Resource type - Journals
eISSN - 1897-5631
pISSN - 0239-8508
DOI - 10.5603/fhc.a2021.0015
Subject(s) - swainsonine , golgi apparatus , endoplasmic reticulum , microbiology and biotechnology , lipid droplet , oil red o , western blot , foam cell , intracellular , vascular smooth muscle , chemistry , lipopolysaccharide , inflammation , biology , biochemistry , endocrinology , cholesterol , immunology , lipoprotein , mesenchymal stem cell , smooth muscle , gene , adipogenesis
Vascular smooth muscle cells (VSMCs)-based foam cell formation is a crucial factor in the atherosclerosis process. We aimed to explore the mechanism of Golgi a-mannosidase II (GMII) effects on the VSMCs-based foam cell formation.