miR-140-5p inhibits the proliferation, migration and invasion of vascular smooth muscle cells by suppressing the expression of NCKAP1 | Zendy

Qing Ma | Zendy; Jiancheng Liu | Zendy; Chunbo Li | Zendy; Dong Wang | Zendy

Open Access

miR-140-5p inhibits the proliferation, migration and invasion of vascular smooth muscle cells by suppressing the expression of NCKAP1

Author(s) -

Qing Ma,

Jiancheng Liu,

Chunbo Li,

Dong Wang

Publication year - 2021

Publication title -

folia histochemica et cytobiologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.384

H-Index - 40

eISSN - 1897-5631

pISSN - 0239-8508

DOI - 10.5603/fhc.a2021.0003

Subject(s) - vascular smooth muscle , cell growth , downregulation and upregulation , aortic dissection , cancer research , dissection (medical) , aorta , cell migration , microbiology and biotechnology , cell , smooth muscle , abdominal aorta , wound healing , pathology , medicine , biology , anatomy , immunology , gene , biochemistry , genetics

The occurrence of aortic dissection is related to the proliferation and metastasis of vascular smooth muscle cells. In our present study, we found that the expression of miR-140-5p was inhibited in the wall of abdominal aorta of aortic dissection patients. However, the mechanism of miR-140-5p in the development of aortic dissection is unclear.

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