Open AccessmiR-140-5p inhibits the proliferation, migration and invasion of vascular smooth muscle cells by suppressing the expression of NCKAP1
Author(s) -
Qing Ma,
Jiancheng Liu,
Chunbo Li,
Dong Wang
Publication year - 2021
Publication title -
folia histochemica et cytobiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.384
H-Index - 40
eISSN - 1897-5631
pISSN - 0239-8508
DOI - 10.5603/fhc.a2021.0003
Subject(s) - vascular smooth muscle , cell growth , downregulation and upregulation , aortic dissection , cancer research , dissection (medical) , aorta , cell migration , microbiology and biotechnology , cell , smooth muscle , abdominal aorta , wound healing , pathology , medicine , biology , anatomy , immunology , gene , biochemistry , genetics
The occurrence of aortic dissection is related to the proliferation and metastasis of vascular smooth muscle cells. In our present study, we found that the expression of miR-140-5p was inhibited in the wall of abdominal aorta of aortic dissection patients. However, the mechanism of miR-140-5p in the development of aortic dissection is unclear.