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The impact of levothyroxine on thyroid autoimmunity and hypothalamic–pituitary–thyroid axis activity in men with autoimmune hypothyroidism and early-onset androgenetic alopecia
Author(s) -
Robert Krysiak,
Karolina Kowalcze,
Bogdan Marek,
Bogusław Okopień
Publication year - 2021
Publication title -
endokrynologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.a2021.0071
Subject(s) - levothyroxine , medicine , endocrinology , thyroid peroxidase , anti thyroid autoantibodies , thyroid , testosterone (patch) , thyroglobulin , autoantibody , antibody , immunology
Administration of testosterone or dehydroepiandrosterone to subjects with low levels of these hormones was found to reduce thyroid antibody titres. Male-pattern baldness is accompanied by mildly increased androgen levels. The present study was aimed at investigating whether early-onset androgenetic alopecia determines the impact of exogenous levothyroxine on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in young men with autoimmune hypothyroidism.

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