Open AccessEvaluation of the risk of fracture in type 2 diabetes mellitus patients with incretins: an updated meta-analysis
Author(s) -
Qingxin Kong,
Qiao Ruan,
Fan Cheng,
Bilin Liu,
Li-Ping Reng,
Xu Wang
Publication year - 2021
Publication title -
endokrynologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.a2021.0031
Subject(s) - sitagliptin , medicine , liraglutide , incretin , meta analysis , type 2 diabetes mellitus , type 2 diabetes , diabetes mellitus , sitagliptin phosphate , subgroup analysis , randomized controlled trial , publication bias , endocrinology
The effect of incretins including dipeptidyl peptidase 4 inhibitors (DPP4-Is) and glucagon-like peptide1 receptor agonists (GLP1-ras) in the treatment of type 2 diabetes increasing the risk of fracture remains controversial. No meta-analysis has been written to discuss this from the prospective interventional studies. The objective was to evaluate the association between the use of incretins and fracture risk.