Open AccessTitin and dystrophin serum concentration changes in patients affected by thyroid disorders
Author(s) -
Ariadna Zybek-Kocik,
Nadia SawickaGutaj,
Remigiusz Domin,
Ewelina SzczepanekParulska,
Tomasz Krauze,
Przemysław Guzik,
Marek Ruchała
Publication year - 2021
Publication title -
endokrynologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.a2020.0083
Subject(s) - medicine , endocrinology , myalgia , thyroid , creatine kinase , muscle weakness , hormone , thyroid function , thyroid hormones
It is well established that thyroid hormones significantly affect skeletal muscle function, causing symptoms like myalgia and muscle weakness. Hypothyroid patients present increased levels of creatine kinase (CK), indicating muscle destruction. Lately, we proposed new serum markers of muscle disturbances in thyroid disorders: titin (TTN) and dystrophin (DMD). The aim of this study is to determine the association between thyroid status, muscle metabolism, and serum levels of TTN and DMD in patients affected by hypoand hyperthyroidism, before and after the treatment.