Open AccessThe effects of mitochondrial dysfunction on energy metabolism switch by HIF-1α signalling in granulosa cells of polycystic ovary syndrome
Author(s) -
Jing Wang,
Xiaohua Wu
Publication year - 2020
Publication title -
endokrynologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.a2020.0002
Subject(s) - polycystic ovary , glycolysis , mitochondrion , medicine , biology , endocrinology , mitochondrial dna , blastocyst , oxidative phosphorylation , citrate synthase , andrology , glut1 , adenosine triphosphate , glucose transporter , microbiology and biotechnology , embryo , metabolism , embryogenesis , insulin resistance , insulin , biochemistry , gene , enzyme
This study aimed to determine the effects of mitochondrial dysfunction on energy metabolism of granulosa cells (GCs) and the competence of oocytes in polycystic ovary syndrome (PCOS).