Open AccessZwiązek polimorfizmu rs 3807337 genu CALD1 z nefropatią cukrzycową w przebiegu cukrzycy typu 1 — wstępne wyniki badania rodzin
Author(s) -
Mirosław Śnit,
Katarzybrdalik,
Michał Długaszek,
Janusz Gumprecht,
Wanda Trautsolt,
Sylwia Górczyńska-Kosiorz,
W Grzeszczak
Publication year - 2017
Publication title -
endokrynologia polska
Language(s) - Polish
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.2017.0003
Subject(s) - offspring , diabetic nephropathy , allele , nephropathy , kidney disease , diabetes mellitus , transmission disequilibrium test , disease , medicine , biology , genetics , haplotype , endocrinology , gene , pregnancy
The worldwide growing burden of diabetes and end-stage renal disease due to diabetic nephropathy has become the reason for research looking for a single marker of chronic kidney disease development and progression that can be found in the early stages of the disease, when preventive action delaying the destructive process could be performed. The aim of the study was to investigate the influence of rs3807337 polymorphism of the caldesmon 1 (CALD1) gene located on the long arm of chromosome 7 encoding for protein that is connected with physiological kidney function on development of diabetic nephropathy.