Open AccessDługotrwała całkowita remisja guza kortykotropowego z komórek Crooke’a po leczeniu temozolomidem
Author(s) -
Maria Kurowska,
Jerzy S. Tarach,
Joanna Malicka,
Grzegorz Zieliński,
Maria Maksymowicz,
Piotr Denew
Publication year - 2016
Publication title -
endokrynologia polska
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.2016.0060
Subject(s) - cushing's disease , medicine , temozolomide , adenoma , progressive disease , acromegaly , refractory (planetary science) , hormone , surgery , urology , disease , chemotherapy , growth hormone , physics , astrobiology
Crooke's corticotropinomas are the unique cause of Cushing's disease. The majority of them are aggressive macroadenomas, refractory to conventional therapy, with a high recurrence rate. The aim of the study was the presentation, in relation to data from the literature, of a case of a patient with ACTH-dependent Cushing's syndrome caused by recurrent Crooke's cells corticotropinoma, who achieved 33-month complete remission after treatment with temozolomide (TMZ).