Open AccessInterferon alpha and rapamycin inhibit the growth of pheochromocytoma PC12 line in vitro
Author(s) -
Ewelina Motylewska,
Hanna Ławnicka,
Magdalena Kowalewicz-Kulbat,
Paulina Sicińska,
Agata Niedziela,
Gabriela Mełeń-Mucha,
H Stępień
Publication year - 2013
Publication title -
endokrynologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.413
H-Index - 27
eISSN - 2299-8306
pISSN - 0423-104X
DOI - 10.5603/ep.2013.0020
Subject(s) - pheochromocytoma , medicine , alpha interferon , endocrinology , interferon , immunology
Pheochromocytomas are benign or malignant neuroendocrine tumours. The unsatisfactory efficacy of the traditional therapeutic methods for patients with metastatic disease results in a continuing search for more effective and targeted agents. Due to the increased vascularisation of these tumours, inhibitors of angiogenesis could be potentially a new group of drugs in pheochromocytoma/paraganglioma therapy.