The effect of varenicline on Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio in healthy smokers and nonsmokers | Zendy

Hasan Arı | Zendy; Selma Arı | Zendy; Selvi Coşar | Zendy; Nuran Celiloğlu | Zendy; İbrahim Aktaş | Zendy; Sencer Çamcı | Zendy; K. Doğanay | Zendy; Ahmet Tütüncü | Zendy; Mehmet Melek | Zendy

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The effect of varenicline on Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio in healthy smokers and nonsmokers

Author(s) -

Hasan Arı,

Selma Arı,

Selvi Coşar,

Nuran Celiloğlu,

İbrahim Aktaş,

Sencer Çamcı,

K. Doğanay,

Ahmet Tütüncü,

Mehmet Melek

Publication year - 2015

Publication title -

cardiology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.573

H-Index - 33

eISSN - 1897-5593

pISSN - 1898-018X

DOI - 10.5603/cj.a2015.0038

Subject(s) - qt interval , medicine , placebo , varenicline , crossover study , cardiology , supine position , anesthesia , heart rate , electrocardiography , nicotine , blood pressure , alternative medicine , pathology

Varenicline could affect the T wave and QT interval. The interval from the peak to the end of the electrocardiographic (ECG) T wave (Tp-e) may correspond to the transmural dispersion of repolarization, and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. In this study, we assessed the effects of varenicline on Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio.

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