Open AccessThe TNF-α, P53 Protein Response and Lung Respiratory Changes Related to Exercise, Chronic Hypoxia and Adiantum capillus-Veneris Supplementation
Author(s) -
Mohammad Hossein Yadegari,
Simin Riahy,
Shadmehr Mirdar,
Gholamreza Hamidian,
Seyed Mohsen Afkhami,
Ayoub Saeidi,
Fatma Rhibi,
Abderraouf Ben Abderrahman,
Anthony C. Hackney,
Hassane Zouhal
Publication year - 2019
Publication title -
advances in respiratory medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 18
eISSN - 2543-6031
pISSN - 2451-4934
DOI - 10.5603/arm.2019.0037
Subject(s) - hypoxia (environmental) , apoptosis , medicine , lung , tumor necrosis factor alpha , respiratory system , endocrinology , biology , chemistry , oxygen , biochemistry , organic chemistry
Evidence suggests that hypoxia and high-intensity exercise training can increase apoptosis of lung cells and Adiantum capillus-veneris (Ac-v) extract can have anti-apoptotic effects. Thus, the aim of the present study was to investigate the effect of chronic hypoxia and the (Ac-v) extraction as a supplement on TNF-a and P53 protein expression as well as the respiratory surface.