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Laboratory comparison of stool processing methods for Xpert® Ultra
Author(s) -
Caitlyn L Jasumback,
Qiniso Dlamini,
Jenna Kahari,
Gugu Maphalala,
M Dlamini,
Gloria Sisi Dube,
Andrew DiNardo,
H. Lester Kirchner,
Anna M. Mandalakas,
Alexander Kay
Publication year - 2021
Publication title -
public health action
Language(s) - English
Resource type - Journals
ISSN - 2220-8372
DOI - 10.5588/pha.20.0079
Subject(s) - medicine , disease
TB disease diagnosis in children is difficult due to non-specific symptoms, paucibacillary disease and the need for invasive procedures to obtain diagnostic specimens. In many settings, these specimens are simply not collected and therefore stool, easily obtained, has emerged as a promising specimen for the diagnosis of child TB. In this study, stool from a healthy adult was spiked with known concentrations of bacille Calmette-Guérin vaccine and tested using the Xpert ® Ultra assay to determine the relative detection and error rate associated with four different published stool processing methods.

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