Open AccessClinical standards for drug-susceptible pulmonary TB
Author(s) -
Onno W. Akkerman,
Raquel Duarte,
Simon Tiberi,
H. Simon Schaaf,
Christoph Lange,
Jan Willem Alffenaar,
Justin Denholm,
Anna Cristina Calçada Carvalho,
Mathieu S. Bolhuis,
Sergey Borisov,
Judith Bruchfeld,
Andrea Maurizio Cabibbe,
José A. Caminero,
Isabel Carvalho,
Jeremiah Chakaya,
Rosella Centis,
Margareth Dalcomo,
Leire Ambrosio,
Martin Dedicoat,
Keertan Dheda,
Kelly E. Dooley,
Jennifer Furin,
José-María García-García,
N.A.H. van Hest,
Bouke C. de Jong,
Xhevat Kurhasani,
Anne-Grete Märtson,
Stellah Mpagama,
Marcela Muñoz Torrico,
Eduardo Nunes,
Catherine W.M. Ong,
Domingo Palmero,
Rovina Ruslami,
Antonia Morita Iswari Saktiawati,
Claude Semuto,
D R Silva,
Rupak Singla,
Ivan Solovič,
Shashikant Srivastava,
Jurriaan E.M. de Steenwinkel,
Alistair Story,
Marieke G G Sturkenboom,
Marina Tadolini,
Z F Udwadia,
A R Verhage,
Jean Pierre Zellweger,
Giovanni Battista Migliori
Publication year - 2022
Publication title -
the international journal of tuberculosis and lung disease/the international journal of tuberculosis and lung disease. articles traduits en français ...
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.103
H-Index - 110
eISSN - 1815-7920
pISSN - 1027-3719
DOI - 10.5588/ijtld.22.0228
Subject(s) - medicine , delphi method , likert scale , health care , public health , gold standard (test) , family medicine , medline , regimen , intensive care medicine , nursing , surgery , statistics , mathematics , political science , law , economics , economic growth
BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice´ for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB). METHODS: A panel of 54 global experts in the field of TB care, public health, microbiology, and pharmacology were identified; 46 participated in a Delphi process. A 5-point Likert scale was used to score draft standards. The final document represents the broad consensus and was approved by all 46 participants. RESULTS: Seven clinical standards were defined: Standard 1, all patients (adult or child) who have symptoms and signs compatible with PTB should undergo investigations to reach a diagnosis; Standard 2, adequate bacteriological tests should be conducted to exclude drug-resistant TB; Standard 3, an appropriate regimen recommended by WHO and national guidelines for the treatment of PTB should be identified; Standard 4, health education and counselling should be provided for each patient starting treatment; Standard 5, treatment monitoring should be conducted to assess adherence, follow patient progress, identify and manage adverse events, and detect development of resistance; Standard 6, a recommended series of patient examinations should be performed at the end of treatment; Standard 7, necessary public health actions should be conducted for each patient. We also identified priorities for future research into PTB. CONCLUSION: These consensus-based clinical standards will help to improve patient care by guiding clinicians and programme managers in planning and implementation of locally appropriate measures for optimal person-centred treatment for PTB.