Open AccessParadox of serial interferon-gamma release assays: variability width more important than specificity size
Author(s) -
Jason E. Stout,
Robert Belknap,
Yig Wu,
Christine Ho
Publication year - 2018
Publication title -
the international journal of tuberculosis and lung disease/the international journal of tuberculosis and lung disease. articles traduits en français ...
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.103
H-Index - 110
eISSN - 1815-7920
pISSN - 1027-3719
DOI - 10.5588/ijtld.17.0650
Subject(s) - medicine , reversion , test (biology) , biology , phenotype , paleontology , biochemistry , gene
Serial screening for latent tuberculous infection (LTBI) is commonly performed in certain populations, such as health care workers. The high apparent conversion rate in some studies of interferon-gamma release assays is puzzling given the claimed high specificity of these tests.