Open AccessInfluence of methotrexate on respiration and ultrastructure of meristematic cells from Allium cepa L. roots
Author(s) -
Maria Podbielkowska,
Maria Wałęza,
Alicja M. Zobel
Publication year - 2014
Publication title -
acta societatis botanicorum poloniae
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 29
eISSN - 2083-9480
pISSN - 0001-6977
DOI - 10.5586/asbp.1981.076
Subject(s) - ultrastructure , meristem , vacuole , allium , respiration , mitochondrion , botany , biology , microbiology and biotechnology , shoot , cytoplasm
It has been demonstrated that methotrexate (an oncostatic preparation) inhibits cellular respiration and reduces the permeability of plasmalemma and tonoplast in cells ofAllium cepa roots. Changes were also found in the ultrastructure of meristematic cells, consisting presence of numerous mitochondria with a dense matrix, a highly developed system of cristae arid an increased number of vacuoles frequently derived from the ER