Open AccessInfluence of cyclophosphamide on respiration and membrane permeability of plant cells
Author(s) -
Maria Podbielkowska,
Alicja M. Zobel,
Maria Wałęza
Publication year - 2014
Publication title -
acta societatis botanicorum poloniae
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 29
eISSN - 2083-9480
pISSN - 0001-6977
DOI - 10.5586/asbp.1980.031
Subject(s) - respiration , cyclophosphamide , membrane permeability , permeability (electromagnetism) , membrane , cell permeability , cell , biophysics , cell membrane , vacuole , chemistry , plant cell , pharmacology , biochemistry , biology , chemotherapy , botany , cytoplasm , genetics , gene
A specific influence of cyclophosphamide, an oncostatic drug of the group of alkylating agents, has been demonstrated on cellular respiration and the permeability of cell membranes. The tested drug under the experimental conditions inhibites cell respiration by about 20-30 per cent as compared with the control. The permeability of the plasmalemma and tonoplast de-creased markedly under the action of cyclophosphamide