Open AccessThe comparison of exacerbation and pneumonia before and after conjugated pneumococcal vaccination in patients with chronic obstructive pulmonary disease, and the effect of inhaled corticosteroid use on results
Author(s) -
Görkem Vayısoğlu Şahin,
Gülistan Karadeniz,
Gülru Polat,
Enver Yalnız,
Aysu Ayrancı,
Fatma Demirci Üçsular,
Mutlu Onur Güçsav
Publication year - 2022
Publication title -
tuberkuloz ve toraks/tüberküloz ve toraks
Language(s) - English
Resource type - Journals
ISSN - 0494-1373
DOI - 10.5578/tt.20229805
Subject(s) - medicine , exacerbation , copd , pneumonia , vaccination , pneumococcal pneumonia , pneumococcal conjugate vaccine , incidence (geometry) , immunology , streptococcus pneumoniae , antibiotics , physics , optics , microbiology and biotechnology , biology
Pneumococcal infections and exacerbations are important causes of mortality and morbidity in chronic obstructive pulmonary disease (COPD). The use of inhaled corticosteroids and pneumococcal vaccination are suggested for the control of the disease progression and exacerbations. The aim of this study is to assess the effect of pneumococcal conjugate vaccine on pneumonia and exacerbation in COPD patients using inhaled corticosteroids (ICSs). The secondary aim is to analyze the effect of ICS use and different ICS types, if administered, on exacerbation and pneumonia incidence in the study population.