Open AccessThe significance of eosinophil and eosinophil lymphocyte ratio (ELR) in predicting response to omalizumab treatment in patients with severe allergic asthma
Author(s) -
Hasan Özgen,
Fatma Merve Tepetam,
İsmet Bulut,
Cihan Örçen
Publication year - 2021
Publication title -
tuberkuloz ve toraks/tüberküloz ve toraks
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.157
H-Index - 18
ISSN - 0494-1373
DOI - 10.5578/tt.20219905
Subject(s) - eosinophil , omalizumab , medicine , asthma , allergy , emergency department , confidence interval , pathological , lymphocyte , gastroenterology , immunology , immunoglobulin e , antibody , psychiatry
Th2/Th1 mix pathological pathway may be seen as a common set of low eosinophilic phenotype in severe allergic asthma. This may affect omalizumab treatment response. In our study, we aimed to investigate whether eosinophil count (EOS) and percentage (EOS%), eosinophil lymphocyte ratio (ELR) and neutrophil lymphocyte ratio (NLR) may predict omalizumab treatment.