Open AccessDetermination of the relationship between major histocompatibility complex alleles andchildhood onset obsessive-compulsive disorder
Author(s) -
HÜSNÜ ÜMİT LÜLEYAP,
GÖKHAN KARACAOĞLAN,
AYŞEGÜL TAHİROĞLU,
AKGÜN YAMAN,
PERÇİN PAZARCI,
SALİH ÇETİNER,
DAVUT ALPTEKİN,
YAŞAR SERTDEMİR,
GÜLŞAH EVYAPAN,
DOĞA LÜLEYAP
Publication year - 2022
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.55730/1300-0144.5333
Subject(s) - allele , major histocompatibility complex , locus (genetics) , medicine , logistic regression , etiology , risk factor , immunology , genetics , gene , immune system , psychiatry , biology
About half of the cases of obsessive-compulsive disorder (OCD) occurring in childhood/adolescence occur with similar symptoms both in childhood and adulthood. Immunologic stress is claimed to be a risk factor in the etiology of childhood onset OCD. Our aim was to elucidate the relationship between childhood onset OCD risk and MHC complex I and II alleles.