Open AccessSerum Krebs von den Lungen-6 concentrations reflect severity of anti-melanoma differentiation-associated protein 5 antibody positive dermatomyositis associated interstitial lung disease
Author(s) -
Yujing Zhu,
Lei Wang,
Yuankai Sun,
Jiajia Wang,
Chengyin Lv,
Hanxiao You,
Lingxiao Xu,
Fang Wang,
Miaojia Zhang,
Wei Tan,
Yao Ke
Publication year - 2022
Publication title -
clinical and experimental rheumatology
Language(s) - German
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 95
eISSN - 1593-098X
pISSN - 0392-856X
DOI - 10.55563/clinexprheumatol/zmn18h
Subject(s) - medicine , interstitial lung disease , dermatomyositis , gastroenterology , risk factor , lung
Rapidly progressive interstitial lung disease (RP-ILD) is a major complication of anti-melanoma differentiation-associated protein 5 antibody positive dermatomyositis (anti-MDA5+DM) with a high mortality rate. The aim of the study is to determine whether serum Krebs von den Lungen-6 (KL-6) could be a prognostic biomarker to predict RP-ILD and prognosis in anti-MDA5+DM patients.