Open AccessExercise pathophysiology differs between connective tissue diseases-associated pulmonary arterial hypertension and idiopathic pulmonary arterial hypertension
Author(s) -
Yi Zhang,
Qi Jin,
Zhihui Zhao,
Qing Zhao,
Xue Yu,
Yan Liu,
Xin Li,
Chansik An,
Xin Ma,
Changming Xiong,
Qian Luo,
Zhihong Liu
Publication year - 2021
Publication title -
clinical and experimental rheumatology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 95
eISSN - 1593-098X
pISSN - 0392-856X
DOI - 10.55563/clinexprheumatol/z0i6ys
Subject(s) - medicine , cardiology , pathophysiology , ctd , hemodynamics , connective tissue disease , pulmonary hypertension , blood pressure , disease , oceanography , autoimmune disease , geology
Previous studies demonstrated that connective tissue diseases-associated pulmonary arterial hypertension (CTD-PAH) had a worse prognosis than idiopathic pulmonary arterial hypertension (IPAH), although the former one had better haemodynamic profiles and right heart function. To find potential explanations for this contradictory phenomenon, we compared the exercise pathophysiology of CTD-PAH with that of IPAH using cardiopulmonary exercise testing (CPET).