Open AccessSARS-CoV-2 in the knee joint: a cadaver study
Author(s) -
Miriam Grassi,
Valeria Giorgi,
Manuela Nebuloni,
Pietro Zerbi,
Maria Rita Gismondo,
Fausto Salaffi,
Piercarlo SarziPuttini,
Sara Giordana Rimoldi,
Alfonso Manzotti
Publication year - 2022
Publication title -
clinical and experimental rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 95
eISSN - 1593-098X
pISSN - 0392-856X
DOI - 10.55563/clinexprheumatol/t1m4y2
Subject(s) - medicine , synovial fluid , knee joint , covid-19 , throat , synovial membrane , pathology , coronavirus , virus , virology , arthritis , surgery , immunology , osteoarthritis , disease , infectious disease (medical specialty) , alternative medicine
Despite the considerable research efforts being made to learn more about COVID-19, little is known about the presence of SARS-CoV-2 genetic material in biological fluids other than respiratory droplets, blood, and feces. The aim of this post-mortem study was to assess the presence of SARS-CoV-2 RNA in the knee synovial fluid, synovial tissue, and bone tissue of COVID-19 patients in order to discover whether the joint is a possible route of transmission during orthopaedic surgical procedures, and clarify the possible role of SARS-CoV-2 as a directly arthritogenic virus.