Open AccessA candidate gene study reveals association between a variant of the SRp55 splicing factor gene and systemic sclerosis
Author(s) -
Eloisa Romano,
Irene Rosa,
Bianca Saveria Fioretto,
Joanna Kosałka-Węgiel,
Elena Sticchi,
Silvia Bellando-Randone,
Mirko Manetti,
Marco MatucciCerinic
Publication year - 2021
Publication title -
clinical and experimental rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 95
eISSN - 1593-098X
pISSN - 0392-856X
DOI - 10.55563/clinexprheumatol/mpgq0y
Subject(s) - genotype , single nucleotide polymorphism , genetic predisposition , allele , medicine , snp , genetics , genetic association , allele frequency , minor allele frequency , biology , gene , disease
To examine the possible implication of the mRNA-binding protein serine/arginine protein 55 (SRp55, also known as SRSF6) rs2235611 single nucleotide polymorphism (SNP) in the genetic predisposition to systemic sclerosis (SSc) susceptibility and clinical phenotype.