Open AccessNaturalistic 6-month antidepressants follow-up in patients with fibromyalgia: impact on somatic and mood spectrum symptoms
Author(s) -
Claudia Carmassi,
Antonio Ciapparelli,
Andrea Cappelli,
Valerio Dell’Oste,
Carlo Antonio Bertelloni,
Claudia Foghi,
Giulia Amatori,
Virginia Pedrinelli,
Laura Bazzichi
Publication year - 2021
Publication title -
clinical and experimental rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.184
H-Index - 95
eISSN - 1593-098X
pISSN - 0392-856X
DOI - 10.55563/clinexprheumatol/j4nkzd
Subject(s) - fibromyalgia , medicine , mood , comorbidity , major depressive disorder , antidepressant , spectrum disorder , mood disorders , clinical global impression , psychiatry , bipolar disorder , physical therapy , clinical psychology , anxiety , alternative medicine , placebo , pathology , hippocampus
Literature shows high rates of comorbidity between fibromyalgia (FM) and mood disorders, especially major depressive disorder (MMD), reported in more than half of the cases. Consistently, patients with FM also present high rates of mood spectrum symptoms, despite scant data are still available on the relationship with antidepressant treatment outcomes. The present study was aimed at exploring the clinical outcome of patients with FM-MDD comorbidity naturalistically treated with antidepressant drugs, besides the relationships between mood spectrum symptoms and the treatment response.