Open AccessPhytochemical Analysis, Antimicrobial and Antioxidant Activity of Crude Extracts from Selected Medicinal Plants.
Author(s) -
Sandipty Kayastha,
Mitesh Shrestha,
Hemanta Kumari Chaudhary,
Krishna K. Shrestha,
Krishna Das Manandhar,
Bal Hari Poudel
Publication year - 2017
Publication title -
international journal of medicine and bi-medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2467-9151
DOI - 10.55530/ijmbiosnepal.v2i3.30
Subject(s) - phytochemical , traditional medicine , antimicrobial , antioxidant , medicinal plants , cytotoxicity , chemistry , extraction (chemistry) , natural product , biology , in vitro , chromatography , biochemistry , medicine , organic chemistry
Background: The search for potential natural bioactive compounds has been carried out for a long time. Researchers working in the field of natural product chemistry are starting to realize the importance of ethnomedicinal knowledge. Methodology: The aim of this study was to carry out preliminary analysis of different plants to understand their therapeutic potential.To this end, methanolic extracts were prepared from four different plant specimens. ntimicrobial, antioxidant and cytotoxicity assays were carried out at different concentrations of the extracts. Results: The highest percentage yield by methanol extraction was achieved from Sapindus murokosii. Phytochemical analysis detected presence of different types of secondary metabolites present in these species. Among the plants selected, Ficus religiosa showed the highest quantity of phenolics and flavonoids content along with lowest IC50 and LC50 for anti-oxidant activity and cytotoxicity assay respectively. Conclusion: The results obtained leads to the conclusion that the selected plants might be possessing strong therapeutics which can be further analyzed for isolation and identification of bioactive compounds.