SARS-CoV-2 screening in pediatric cancer patients before hospitalization for chemotherapy infusion | Zendy

María Victoria Cabarcos | Zendy; Myriam Onoratelli | Zendy; Mariano N Lorenzo | Zendy; Sabrina Guzmán | Zendy; M. Foronda Rios | Zendy; Marina Spilotti | Zendy; Sandra Gómez | Zendy; Lidia Fraquelli | Zendy

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SARS-CoV-2 screening in pediatric cancer patients before hospitalization for chemotherapy infusion

Author(s) -

María Victoria Cabarcos,

Myriam Onoratelli,

Mariano N Lorenzo,

Sabrina Guzmán,

M. Foronda Rios,

Marina Spilotti,

Sandra Gómez,

Lidia Fraquelli

Publication year - 2022

Publication title -

archivos argentinos de pediatria

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.236

H-Index - 19

eISSN - 1668-3501

pISSN - 0325-0075

DOI - 10.5546/aap.2022.eng.118

Subject(s) - medicine , asymptomatic , chemotherapy , confidence interval , covid-19 , observational study , disease , pediatrics , infectious disease (medical specialty)

An observational, prospective study was carried out at Hospital Garrahan. Its objectives were to establish the rate of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children with cancer and/or their caregivers during hospitalization for chemotherapy, and describe the impact of ongoing treatment among those positive for SARS-CoV-2 or with symptoms compatible with infection during hospitalization. Patients with onco-hematological disease and their caregivers were included. A reverse transcription polymerase chain reaction for SARS-CoV-2 was done. A total of 733 hospitalizations were analyzed. The SARS-CoV-2 positivity rate was 2.2% (95% confidence interval: 1.35-3.52). All patients with a detectable test result completed chemotherapy. Also, 7.7% of patients developed symptoms compatible with a suspected case although they had an undetectable test result, and 77% of them were able to continue treatment.

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