Consenso sobre el tratamiento del síndrome inflamatorio multisistémico asociado a COVID-19 | Zendy

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Consenso sobre el tratamiento del síndrome inflamatorio multisistémico asociado a COVID-19

Author(s) -

Dra Gabriela,

Dra Ensinck,

Dra Gregorio,

Dra Rosana,

María Flores,

Dra Cecilia,

I Crowe,

Dra Paola,

Clerico Mosina,

Dra Curi,

Jorro Facundo,

Guillermo Kohn Loncarica,

Dra Sofía Grinenco,

Dra Ríos,

Dra Claudia González,

D.V. Zaslavsky,

Leonardo De Lillo,

Eduardo Vainstein,

Luis Urrutia,

Dra María,

P Della Latta,

Dra Falaschi,

Dra Silvina Ruvinsky,

Dra Tapponier,

Dra Calvari,

Dra Liliana,

E Asis Comité De Dermatología,

F Scacchi,

Dra Giachetti,

Dra Castro,

F Greco,

Dra Barabini,

Dra Larralde,

Dra Limanski,

L Donato,

Dra Buscio,

Dra Galvagno,

D. Laurino,

Dra Labán,

Dra Varone,

Dra Ana,

Mariella Lorusso,

Dra Estela De Carli,

Norberto Carli,

L Lisdero,

Victoria M.L. Cohen,

Dra Silvina,

N Rodríguez,

Gustavo Pereyra,

D. V. Rebollo,

Dra Cascón,

Dra Nani,

Dra Ciriaci,

Dra Martinitto,

D. J. Palladino,

Dra Rubiños

Publication year - 2021

Publication title -

archivos argentinos de pediatria

Language(s) - Spanish

Resource type - Journals

SCImago Journal Rank - 0.236

H-Index - 19

eISSN - 1668-3501

pISSN - 0325-0075

DOI - 10.5546/aap.2021.s198

Subject(s) - medicine , humanities , philosophy

The pandemic caused by the SARS-CoV-2 virus declared by the WHO in March 11th 2020, affects a small number of pediatric patients, who mostly present mild respiratory compromise and favorable evolution. However began to be observed in previously healthy children, an increase in cases defined as "Multisystemic Inflammatory Syndrome" (MIS-C) or "Kawasaki-like" post-COVID 19 (KLC) that evolve to shock and require hospitalization in the Pediatric Intensive Care Unit. MIS-C and KL-C are characterized by fever; signs of inflammation, gastrointestinal symptoms, and cardiovascular dysfunction, associated with sever forms of presentation with higher incidence of hypotension and/or shock. In the laboratory, markers of inflammation, hypercoagulability and myocardial damage are observed. Firstline drug treatment consists of intravenous immunoglobulin plus oral acetylsalicylic acid. A multidisciplinary approach is recommended for an accurate diagnosis and an early and effective treatment, in order to reduce morbidity and mortality.

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