Open AccessCytokine responses to symbiotic and lactoferrin combination in very low birth weight neonates: a randomized control trial
Author(s) -
Ozge Serce Pehlevan,
Derya Benzer,
Tuğba Gürsoy,
Esin Aktaş Çetin,
Güner Karatekın,
Fahri OvaliMD
Publication year - 2020
Publication title -
archivos argentinos de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2020.eng.e8
Subject(s) - lactoferrin , necrotizing enterocolitis , bifidobacterium , medicine , placebo , population , cytokine , randomized controlled trial , probiotic , bacteroides , gastroenterology , immunology , lactobacillus , physiology , biology , food science , bacteria , biochemistry , genetics , alternative medicine , environmental health , pathology , fermentation
Probiotics and prebiotics, which are multifunctional agents, have potential benefits in chronic mucosal inflammation, including the prevention of necrotizing enterocolitis. However, the mechanisms and the results of these immunomodulatory effects are not clear. This study aimed to investigate the cytokine response to the combination of Lactobacillus and Bifidobacterium together with fructo- and galacto-oligosaccharides (symbiotic) and lactoferrin in very low birth weight neonates.