Open AccessStenotrophomonas maltophilia bacteremia in children - A 10-year analysis
Author(s) -
Ayşe Büyükçam,
Asiye Bıçakçıgil,
Ali Bülent Cengiz,
Banu Sancak,
Mehmet Ceyhan,
Ateş Kara
Publication year - 2020
Publication title -
archivos argentinos de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2020.eng.e317
Subject(s) - stenotrophomonas maltophilia , bacteremia , gram negative bacterial infections , stenotrophomonas , medicine , microbiology and biotechnology , biology , pseudomonas , bacteria , pseudomonas aeruginosa , antibiotics , genetics
Stenotrophomonas maltophilia is a multidrug-resistant, Gramnegative, and biofilm-forming pathogen. Information is limited concerning S. maltophilia bacteremia in children. Clinical data and microbiological test results collected in a tertiary children's hospital over a ten-year period were reviewed. Children 0-18 years old who had positive clinical specimen, blood and/or catheter cultures were included. We identified 20 S. maltophilia isolates from 12 pediatric patients with confirmed infections. The median age was 28 months (range: 3.1-187.3). The rate of previous use of antimicrobial therapy was 83 %. The median antibiotic number was 3 (range: 0-7) within 30 days prior to onset of S. maltophilia bacteremia. Catheter related infection was the main infectious source (66.6 %). The mortality rate was 33.3 %. The death of two non-survivors was associated with pneumonia. S. maltophilia should be considered a breakthrough agent for bacteremia in children with underlying disease exposed to broad-spectrum antibiotics during long-term hospitalization.