Open AccessEfficacy and safety of caspofungin in children: systematic review and meta-analysis
Author(s) -
María Teresa Rosanova,
David Bes,
Pedro Serrano Aguilar,
Leticia Cuéllar-Pompa,
Norma Sberna,
Roberto Lede
Publication year - 2016
Publication title -
archivos argentinos de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2016.eng.305
Subject(s) - jadad scale , caspofungin , medicine , antifungal , off label use , randomized controlled trial , intensive care medicine , pediatrics , amphotericin b , dermatology , cochrane library
Invasive fungal infections are a significant cause of morbidity and mortality in children. Caspofungin is an echinocandin used as an alternative treatment in the prevention and/or treatment of certain invasive fungal infections in children, although compared to the standard treatment there is little evidence on its efficacy and safety.