Open AccessNeumonía necrotizante asociada a infección por influenza A H1N1 en un niño con mucopolisacaridosis tipo II. Caso clínico
Author(s) -
Daniel A. Huillca-Huerta,
Luis G Yllescas-Estela,
Elizabeth A Huerta-Medina,
Pedro E San Martín-Howard
Publication year - 2015
Publication title -
archivos argentinos de pediatría
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2015.e1
Subject(s) - medicine , hunter syndrome , mucopolysaccharidosis type ii , pneumonia , heparan sulfate , mucopolysaccharidosis , gastroenterology , disease , enzyme replacement therapy , heparin
Mucopolysaccharidosis type II (MPS II) is an X-linked recessive disorder characterized by a deficiency of the enzyme iduronate-2-sulfatase leading to a multisystem involvement by tissue accumulation of glycosaminoglycans heparan and dermatan sulfate. We report a case of a 9-year-old boy diagnosed with mucopolysaccharidosis type II at 4 years of age, classified as severe variant. He presented necrotizing pneumonia associated with influenza A H1N1 infection, requiring mechanical ventilation for 1 month and 10 days. This case emphasizes the importance of healthcare workers to be aware of potentially lethal complications in patients with MPS II, such as influenza A H1N1 infection, which in turn may be associated with necrotizing pneumonia.