Clinical outcome of neonates with nosocomial suspected sepsis treated with cefazolin or vancomycin. A non-inferiority, randomized, controlled trial | Zendy

José Ceriani | Zendy; José Ceriani Cernadas | Zendy; Silvia Fernández Jonusas | Zendy; Maritza Márquez | Zendy; Armando Garsd | Zendy; Gonzalo Mariani | Zendy; Amorina Pardo | Zendy; Adrián Aguilar | Zendy; Andrea Lew | Zendy; Marcelo Armadans | Zendy

Open Access

Clinical outcome of neonates with nosocomial suspected sepsis treated with cefazolin or vancomycin. A non-inferiority, randomized, controlled trial

Author(s) -

José Ceriani,

José Ceriani Cernadas,

Silvia Fernández Jonusas,

Maritza Márquez,

Armando Garsd,

Gonzalo Mariani,

Amorina Pardo,

Adrián Aguilar,

Andrea Lew,

Marcelo Armadans

Publication year - 2014

Publication title -

archivos argentinos de pediatria

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.236

H-Index - 19

eISSN - 1668-3501

pISSN - 0325-0075

DOI - 10.5546/aap.2014.eng.308

Subject(s) - cefazolin , medicine , randomized controlled trial , vancomycin , sepsis , intensive care medicine , anesthesia , surgery , antibiotics , staphylococcus aureus , genetics , bacteria , microbiology and biotechnology , biology

Nosocomial infections are a major problem in Neonatal Intensive Care Units. Coagulase negative Staphylococcus (CONS) is the most common causative agent. We evaluated the efficacy of cefazolin versus vancomycin as initial therapy for neonates with presumptive clinical signs of nosocomial sepsis probably caused by CONS.

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