Open AccessClinical outcome of neonates with nosocomial suspected sepsis treated with cefazolin or vancomycin. A non-inferiority, randomized, controlled trial
Author(s) -
José M Ceriani Cernadas,
Silvia Fernández Jonusas,
Maritza Márquez,
Armando Garsd,
Gonzalo Mariani
Publication year - 2014
Publication title -
archivos argentinos de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2014.eng.308
Subject(s) - cefazolin , medicine , randomized controlled trial , vancomycin , sepsis , intensive care medicine , anesthesia , surgery , antibiotics , staphylococcus aureus , genetics , bacteria , microbiology and biotechnology , biology
Nosocomial infections are a major problem in Neonatal Intensive Care Units. Coagulase negative Staphylococcus (CONS) is the most common causative agent. We evaluated the efficacy of cefazolin versus vancomycin as initial therapy for neonates with presumptive clinical signs of nosocomial sepsis probably caused by CONS.