Open AccessSevere Staphylococcus aureus infection in three pediatric intensive care units. Analysis of cases of necrotizing pneumonia
Author(s) -
Pedro Taffarel,
Germán Bonetto,
Matías Penazzi,
Facundo Jorro Barón,
Silvia Saenz,
Macarena Uranga,
Eduardo Mari,
Rosana Pereda,
Gustavo Debaisi
Publication year - 2014
Publication title -
archivos argentinos de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2014.eng.163
Subject(s) - medicine , staphylococcus aureus , pneumonia , methicillin resistant staphylococcus aureus , intensive care , intensive care medicine , bacteria , biology , genetics
Staphylococcus aureus frequently affects human beings. Among clinical manifestations, necrotizing pneumonia is associated with a high mortality rate. Our objective is to describe the progress of severe Staphylococcus aureus infections in three intensive care units and analyze cases ofnecrotizing pneumonia in the period ranging from January 2011 to March 2013. Forty-three patients were studied, 76.7% had a community-acquired infection, and 31 had community-acquired methicillin-resistant Staphylococcus aureus. The main reason for admission was respiratory failure. Bacteremia was confirmed in 55.8% of cases. Mechanical ventilation was required in 86% of admitted patients, while 27 patients developed septic shock. The length of stay in the intensive care unit was 13 (5-25) days, and the mortality rate was 14%. Necrotizing pneumonia was observed in 51% of cases. Conclusion. A high rate of community-acquired infection was identified. Necrotizing pneumonia was associated with a worse clinical course.