Open AccessFalla de respuesta anticorpórea frente a antígenos polisacáridos. Serie de casos
Author(s) -
Diana Cabanillas,
V. D’Alessandro,
Graciela Diez,
Lorena Regairaz
Publication year - 2014
Publication title -
archivos argentinos de pediatría
Language(s) - Spanish
Resource type - Journals
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2014.e247
Subject(s) - medicine , antibody , immunology , antigen
Specific antibody deficiency is a common antibody immunodeficiency defined as a poor antibody response to pneumococcal polysaccharides antigens present in the 23-valent pneumococcal vaccine, with normal immunoglobulins and normal response to protein antigens. Clinical manifestations include recurrent sinopulmonary infections, severe infections and asthma. The aim of this presentation is to describe clinical manifestations and evolution of a cohort of children with specific antibody deficiency diagnosed and followed in our center between 1998 and 2012.