Open AccessInfecciones graves por Staphylococcus aureus: características clínicas, sensibilidad antibiótica y uso de antimicrobianos. Serie de casos
Author(s) -
Juan Eduardo Ves Losada,
Ana Paula Graziano,
Maximiliano De Abreu,
Miriam Blanco,
Lorena Frutos,
Lucas Tula,
César Montali,
Pablo García Munitis
Publication year - 2014
Publication title -
archivos argentinos de pediatría
Language(s) - Spanish
Resource type - Journals
eISSN - 1668-3501
pISSN - 0325-0075
DOI - 10.5546/aap.2014.e152
Subject(s) - staphylococcus aureus , clindamycin , medicine , antibiotics , vancomycin , rifampicin , methicillin resistant staphylococcus aureus , microbiology and biotechnology , bacteria , biology , genetics
Infectious due to methicillin-resistant community acquired Staphylococcus aureus is a public health problem of varying magnitude in different geographical areas of the world, representing a major burden on health systems. The debate on the initial empiric antibiotic therapy remains open. We present a case series of hospitalized patients with severe Staphylococcus aureus infections admitted to the pediatric intermediate care unit of Hospital El Cruce. Between May 2008 and December 2010, 43 patients were admitted. Sixty nine percent of isolated Staphylococcus aureus were methicillin-resistant. Although the difference was not statistically significant, methicillin-resistant Staphylococcus aureus infections required more days of hospitalization in critical care unit and developed more secondary sites of infection. Vancomycin, rifampicin and clindamycin were the most commonly prescribed antibiotics. There was a high resistance of Staphylococcus aureus to p-lactams in the series.