Lesión renal aguda secundaria a lisis tumoral inducida por esteroides en una adolescente con leucemia linfoblástica aguda. Rol de la alcalinización urinaria y diálisis peritoneal | Zendy

Gustavo H. Marín | Zendy

Open Access

Lesión renal aguda secundaria a lisis tumoral inducida por esteroides en una adolescente con leucemia linfoblástica aguda. Rol de la alcalinización urinaria y diálisis peritoneal

Author(s) -

Gustavo H. Marín

Publication year - 2012

Publication title -

archivos argentinos de pediatria

Language(s) - Spanish

Resource type - Journals

SCImago Journal Rank - 0.236

H-Index - 19

eISSN - 1668-3501

pISSN - 0325-0075

DOI - 10.5546/aap.2012.e118

Subject(s) - medicine , nephrocalcinosis , tumor lysis syndrome , peritoneal dialysis , lymphoblastic leukemia , acute kidney injury , urinary system , tubulopathy , gastroenterology , kidney disease , kidney , leukemia , chemotherapy

An adolescent with acute lymphoblastic leukemia developed an early and severe tumor lysis syndrome with acute kidney injury after a low and single dose of steroids. Renal dysfunction was attributed primarily to phosphate nephropathy with nephrocalcinosis due to extreme elevations of phosphate in blood. Urinary alkalinization probably contributed to this development. We used peritoneal dialysis with resolution of nephrocalcinosis and normalization of creatinine clearance.

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