Open AccessPesquisa audiológica y molecular para pérdida auditiva por mutación 35delG en el gen de la conexina 26 e infección congénita por citomegalovirus
Author(s) -
Edgardo Raúl Streitenberger,
Ariel Ignacio Suárez,
María Verónica Masciovecchio,
Diana Laurnagaray,
Ernesto Alda
Publication year - 2011
Publication title -
archivos argentinos de pediatria
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 19
ISSN - 0325-0075
DOI - 10.5546/aap.2011.479
Subject(s) - medicine , humanities , philosophy
Hearing loss may be attributed to genetic and environmental factors. Mutations in the gene of the CX26 protein (connexin 26), are responsible for 30-80% of all cases of non-syndromic profound hearing loss. The 35delG is the most frequent variant in the caucasian population. As to environmental factors, the cytomegalovirus (CMV) is the main cause of congenital infection.