Open AccessAssociation of rare disease and acute intoxication – case report
Author(s) -
Radu Alexandru Macovei,
Radu C. Tincu,
M Tudosie
Publication year - 2018
Publication title -
romanian journal of military medicine
Language(s) - English
Resource type - Journals
eISSN - 2501-2312
pISSN - 1222-5126
DOI - 10.55453/rjmm.2018.121.1.8
Subject(s) - medicine , coma (optics) , anesthesia , hypothermia , dysarthria , bradycardia , etiology , nystagmus , ataxia , asystole , apnea , depression (economics) , disease , benzodiazepine , intensive care medicine , pediatrics , blood pressure , heart rate , physics , receptor , macroeconomics , psychiatry , optics , economics , radiology
Benzodiazepine overdose has various clinical manifestation, mainly regarding the central nervous system (CNS), cardiac and respiratory side effects, but rarely results in significant morbidity and mortality. Acute benzodiazepine poisoning results in dizziness, ataxia, nystagmus, dysarthria, hypoxia, hypothermia, bradycardia, hypotension, apnea, pulmonary aspiration, respiratory depression, coma, cardiopulmonary arrest and death. Anyway, deep nonresponsive coma should be investigated for additional etiologies. On the other hand, human transmissible prion disease has a fatal outcome with no specific treatment.